【摘要】 目的采用CT灌注成像(CTP)定量评估急性缺血性脑梗死(AIS)患者侧支循环动态变化情况。方法分别以CTP达峰时间/密度比值变化评分作为定量指标评估AIS患者侧支循环;分析侧支循环变化情况与梗死指标间的相关性。结果在AIS患者中,梗死指标与对比剂达峰时间/密度比值变化评分呈不同程度相关,且与达峰密度比值变化评分相关性更显著。结论 CTP可提供定量评估侧支循环变化的影像学指标,对比剂达峰密度较达峰时间评估侧支循环更准确。更多还原

【Abstract】 Aim To quantitatively evaluate the changes of collateral circulation in patients with acute ischemic stroke(AIS) by using computed tomographic perfusion(CTP). Methods The collateral circulation of AIS patients was quantitatively evaluated by grading the changes of collateral circulation with measurement of contrast peak time delay/density respectively. The correlation between infarct biomarkers and quantitative changes of collateral circulation was studied. Results In patients with AIS, infarct biomarkers achieved varying degrees of correlation with score changes of contrast peak time/density ratio, and score changes of contrast peak density ratio showed stronger correlation with infarct biomarkers. Conclusion CTP could provide imaging makers to evaluate collateral circulation quantitatively. Compared to contrast peak time, contrast peak density showed better association with collateral circulation.更多还原