Hypopharyngeal carcinoma is the worst malignant tumor in the head and neck squamous cell carcinoma,which has the worst prognosis.As the hypopharynx has a rich lymphatic network,cervical lymph node metastasis is very easy to occur.Castleman disease is vascular follicular lymphnode hyperplasia,a rare chronic lymphoproliferative disease of unknown cause.In the diagnosis of Castleman disease,attention should be paid to the differential diagnosis of head and neck malignant tumors.