节点文献
生命的镶嵌性
Mosaicism of Life
【摘要】 研究者过去认为,多细胞生物体内所有体细胞的基因组序列完全一样,都来自受精卵的基因组;机体的每种组织内同类型的细胞之间是高度一致的,但近年来的研究揭示,大多数细胞的基因组序列存在着各种各样的体细胞变异,组织中同一类型的细胞之间也存在着明显的结构或功能上的差别。
【Abstract】 Previous studies suggest that all somatic cells of a multicellular organism contain the same genome that comes from a fertilized egg and each type of them in a tissue is highly homogeneous. However, recent researches show that different somatic cells may have different genomes with various mutations and copy number variations, and each type of them presents heterogeneous property.
- 【文献出处】 科学 ,Science , 编辑部邮箱 ,2018年01期
- 【分类号】Q23
- 【下载频次】66