【摘要】 目的探讨脊髓型颈椎病(CSM)患者脊髓MRI T2加权像(MRI T2WI)高信号改变与血清维生素B12水平之间的关系。方法 2007年6月—2010年6月,本院共收治确诊CSM患者91例,按照脊髓MRI T2WI有无高信号改变对患者进行分组,有高信号改变为研究组(47例),无高信号改变为对照组(44例)。对患者的血清维生素B12水平进行检测,并分析维生素B12水平与MRI T2WI高信号、性别、年龄、脊髓受压程度之间的关系。结果有高信号改变患者血清维生素B12水平明显降低,与无高信号改变患者相比差异具有统计学意义(P<0.05)。高信号改变和维生素B12水平下降具有相关性。结论脊髓MRI T2WI高信号改变和血清维生素B12水平存在相关性,血清维生素B12水平可能与CSM的发生相关。更多还原

【Abstract】 Objective To investigate the relationship between the increased signal intensity on MRI T2 weighted image(MRI T2 WI) and serum vitamin B12 level in cervical spondylotic myelopathy(CSM). Methods From June 2007 to June 2010,there were 91 patients diagnosed as having CSM. The patients were divided into 2 groups according to the signal intensity on MRI T2 WI,patients with high signal serving study group(47 cases),those without high signal as control group(44 cases). Serum vitamin B12 levels were detected in these patients. The relationship between the vitamin B12 level and the increased signal intensity on MRI T2 WI,gender,age and spinal cord compression degree were analyzed. Results The serum vitamin B12 levels in patients with high signal change were significantly lower than those without high signal changes and the difference was statistically significant(P < 0.05). Statistically significant linear relationship was demonstrated between Vitamin B12 and the increased signal intensity. Conclusion The increased signal intensity on MRI T2 WI is related to serum vitamin B12,and the latter may be a prognostic factor for patients with CSM.更多还原