【摘要】 目的观察瑞芬太尼复合丙泊酚用于无痛碘油输卵管造影(HSG)的临床效果及安全性。方法选择2014年1月至2016年1月该院妇产科进行HSG的98例不孕患者作为研究对象,采用随机数字表法分为试验组和对照组各49例。试验组患者采用瑞芬太尼复合丙泊酚进行麻醉,对照组患者采用丙泊酚进行麻醉。记录并分析两组患者入室(T1)、给予麻醉药物2 min后(T2)、扩张宫颈(T3)、置入微导管(T4)及检查结束时(T5)5个时间点的平均动脉压(MAP)、心率、血氧饱和度(SpO2)、术后不良反应发生率、苏醒后下腹视觉模拟评分(VAS评分)、定向力恢复时间、Riker镇静躁动评分、术中知晓情况、患者满意度及医生满意度。结果在T2时间点,试验组患者的心率明显低于对照组,MAP、SpO2明显高于对照组患者,差异均有统计学意义(P<0.05);两组患者苏醒后下腹VAS评分及术中知晓情况比较,差异无统计学意义(P>0.05);试验组患者术中呼吸抑制、体动反应及术后恶心的发生率明显低于对照组,需麻醉医生干预次数明显少于对照组,术后定向力恢复时间、Riker镇静躁动评分明显优于对照组,差异均有统计学意义(P<0.05)。结论瑞芬太尼复合丙泊酚用于HSG镇静效果满意、患者血流动力学稳定、术后恢复时间短、躁动发生少,安全性可靠,镇静效果与安全性均优于单独使用丙泊酚。更多还原

【Abstract】 Objective To observe the clinical effect of remifentanil combined with propofol in the treatment of painless hysterosalpinography(HSG).Methods Totally 98 patients with infertility were treated with HSG from January 2014 to January 2016 as the observation objects.Using random number table method,there were49 cases in test group and 49 cases in the control group.In the test group,remifentanil combined with propofol was used for anesthesia.Patients in the control group were treated with propofol.Mean arterial pressure(MAP)at 5 time points after entering the room(T1),2 minutes after anesthesia(T2),dilating the cervix(T3),placing the microcatheter(T4),and at the end of the examination(T5),heart rate,blood oxygen saturation(SpO2),postoperative adverse reactions,visual simulation score of abdomen after recovery(VAS score),the recovery time of orientation force,Riker calm and rest score,intraoperative awareness,patient satisfaction and physician satisfaction in each group were recorded and analyzed.Results At T2 time,the heart rate of the test group was significantly lower than control group,MAP and SpO2 was significantly higher than the control group of patients,the differences were statistically significant(P<0.05).Comparison of VAS score and intraoperative awareness of the two groups after awakening,the differences were not statistically significant(P>0.05).The incidence of intraoperative respiratory depression and physical response and postoperative nausea was significantly lower in the test group than the control group,the number of interventions required by anesthesiologists was significantly less than the control group,postoperative the recovery time of orientation force and Riker calm and restless score was significantly better than the control group,the differences were statistically significant(P<0.05).Conclusion Remifentanil combined with propofol for the treatment of HSG has better effect,hemodynamic stability,short postoperative recovery time,less turbulence.The sedative effect and safety are better than propofol.更多还原