【摘要】 目的探讨经桡动脉入路施行弓上动脉内支架成形术的安全性、可靠性和有效性。方法收集2012年1月至2016年1月连续收治的325例弓上动脉闭塞/狭窄患者临床资料,根据患者需求分别予以经桡动脉入路(52例)、经股动脉入路(273例)弓上动脉内支架成形术。观察并记录两组患者穿刺结果、手术结果、手术持续时间、术中出血量、术后并发症、术后卧床时间、平均住院时间。结果两组患者穿刺成功率、手术成功率、术中出血量差异无统计学意义(P>0.05)。手术持续时间≤30 min患者在桡动脉入路组占73.1%(38/52),股动脉入路组占43.2%(118/273),差异有显著统计学意义(P<0.0001)。术后桡动脉入路组穿刺点出血8例、穿刺部位血肿1例,并发症发生率为17.3%(9/52),股动脉入路组穿刺点出血23例、穿刺部位血肿7例、穿刺部位疼痛1例、脑出血1例,并发症发生率为11.7%(32/273),差异无统计学意义(χ~2=1.236,P=0.266)。桡动脉入路组患者术后即可下床活动。两组患者平均住院时间差异无统计学意义(P>0.05)。结论经桡动脉入路和经股动脉入路弓上动脉内支架成形术临床治疗安全可靠、效果好,经桡动脉入路可作为经股动脉入路替代术式。更多还原

【Abstract】 Objective To investigate the safety, reliability and effectiveness of supra-aortic artery stenting angioplasty via transradial access in treating supra-aortic artery occlusion or stenosis. Methods The clinical data of 325 consecutive patients with supra-aortic artery occlusion or stenosis, who were admitted to authors’ hospital during the period from January 2012 to January 2016 to receive stenting angioplasty, were retrospectively analyzed. According to patient’s own will, the 325 patients were divided into transradial access group(n=52) and transfemoral access group(n=273). The results of the puncturing, the operative results, the duration of operation, the amount of intraoperative blood loss, the postoperative complications, the time of postoperative rest in bed, the average time of hospitalization of both groups were recorded. Results No statistically significant differences in the success rate of puncturing, the success rate of operation and the amount of intraoperative blood loss existed between the two groups(P>0.05). In 73.1% of patients(38/52) of the transradial access group the duration of operation was ≤30 min, while only in 43.2% of patients(118/273) of the transfemoral access group the duration of operation was ≤30 min, the difference between the two groups was statistically significant(P<0.000 1). After the operation, in transradial access group puncture point bleeding was seen in 8 patients and hematoma at the puncture site in one patient, the complication rate was17.3%(9/52), while in transfemoral access group puncture point bleeding was observed in 23 patients,hematoma at the puncture site in 7 patients, pain of puncture site in one patient, and cerebral hemorrhage in one patient, the total complication rate was 11.7%(32/273); but the difference between the two groups was not statistically significant(χ~2=1.236, P=0.266). Patients in the transradial access group could get out of bed immediately after the operation. No statistically significant difference in the average time of hospitalization existed between the two groups(P >0.05). Conclusion In performing endovascular stenting angioplasty for supra-aortic artery occlusion or stenosis, both transradial access and transfemoral access are safe, reliable and effective. Transradial access can be used as a replacement of transfemoral access.更多还原