【摘要】 目的:探讨山莨菪碱注射液湿敷治疗股静脉置管致皮下血肿的临床效果,为其临床推广应用提供依据。方法:选取接受静脉化疗行股静脉置管时发生局部血肿的癌症患者93例,按随机数字表法随机分为观察组48例、对照组45例。观察组采用山莨菪碱注射液湿敷血肿处,对照组采用50%硫酸镁湿敷。观察两组患者止痛起效时间、治疗24h后两组镇痛效果及持续治疗72 h后血肿消退的效果。结果:观察组和对照组止痛起效时间分别为(17.1±1.6)min和(45.9±1.8)min,观察组起效比对照组快,差异具有统计学意义(P<0.05);治疗24 h后,观察组60%患者无痛,40%患者有轻、中度疼痛;对照组11%患者无痛,89%患者有轻、中、重度疼痛,差异有统计学意义(P<0.05)。治疗72 h后总有效率观察组为100%、对照组为86%,差异具有统计学意义(P<0.05)。结论:山莨菪碱注射液湿敷治疗股静脉置管致皮下血肿疗效显著,操作简单,安全可靠,可在临床推广应用。更多还原

【Abstract】 Objective To study the clinical effect of anisodamine injection in the treatment of subcutaneous hematoma caused by femoral vein catheterization,and to provide the basis for its clinical application. Method 93 patients with local hematoma who underwent intravenous catheterization in our hospital were randomly divided into observation group(n = 48) and control group(n= 45) according to random number table. The observation group was treated with anisodamine injection in the hematoma. The control group was wet-deposited with 50% magnesium sulfate. The analgesic effect of the two groups was observed 24 hours after treatment and the effect of hematoma subsided after 72 hours of continuous treatment. Results The onset time of analgesia in observation group and control group was(17. 1 ± 1. 6) min and(45. 9 ± 1. 8) min respectively,and the onset of treatment in observation group was faster than that in control group(P<0. 05). After treatment for 24 h,60% Pain,40% of patients had mild to moderate pain; 11% of patients in the control group painless,89% of patients with mild,moderate and severe pain,the difference was statistically significant(P<0. 05). Thetotal effective rate was 100% in the observation group and 86% in the control group(P<0. 05). Conclusion Anisodamine injection in the treatment of subcutaneous hematoma caused by femoral vein catheter is effective,simple,safe and reliable,can be widely used in clinical practice.更多还原