Programmed cell death 4(PDCD4) is a novel gene obtained during the study of apoptotic mechanisms. It is widely expressed in various tissues and organs of healthy individuals. Its expression is lost or reduced in various tumors, and forced expression can markedly inhibit tumor growth or migration and invasion; therefore, PDCD4 has been regarded as a new tumor suppressor gene.Increasing research has suggested that PDCD4 not only plays an antitumor role but also is involved in inflammatory disease, thereby act...
【更新日期】
2018-12-20
【分类号】
R730.2;R364.5
【正文快照】
PDCD4在炎症和肿瘤中的作用和机制贾玉峰,陈晓彤,张利宁*山东大学基础医学院医学免疫学系,济南250012*联系人, E-mail:zhanglining@sdu.edu.cn程序性细胞死亡因子4(programmed cell death 4,PDCD4)是1995年日本学者Shibahara等人[1]在研究细胞凋亡机制时,在诱导凋亡的鼠细胞中?
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