【摘要】 目的基于社会网络分析技术,探究猪囊尾蚴感染在四川省藏族农区学校儿童中的传播特点,并分析该地学校儿童整体社会网络结构,为进一步制订学校儿童猪囊尾蚴感染的预防与控制策略提供实证依据。方法以四川省凉山州藏族农区两所猪囊尾蚴感染严重的寄宿制和走读制小学为调研现场,整群抽取两所小学的所有学校儿童作为研究对象。由经过统一培训的调查员收集学校儿童的社会网络信息,主要包括教室座次、宿舍床位、最好的玩伴、经常一起吃饭的同伴以及分享零食的小伙伴;由寄生虫专业人员采集学校儿童的粪样、血样,并进行实验室检测。采用社会网络分析技术对学校儿童中猪囊尾蚴"传染源-暴露感染者"网络及学校儿童的整体社会网络进行分析。结果共收集644例学校儿童的社会网络资料,其中粪检猪带绦虫抗体阳性率为6.11%,血清学检测抗体阳性率为13.25%。学校儿童猪囊尾蚴"传染源-暴露感染者"网络呈现出以传染源为中心,暴露感染者向传染源聚集的现象;其中寄宿制小学主要以宿舍聚集性的传播为主,走读制小学主要以最好的玩伴间的传播为主。两所小学的整体社会网络分析,网络中均存在"核心人物"(点度中心度高,即该节点与网络中的其他节点拥有的关系数多)、"信息传播者"(接近中心度高,网络中某一节点与其他节点之间的接近程度高)及"信息枢纽"(中介中心度高,一个节点在多大程度上位于其他"点对"之间)。结论在同一宿舍的密切接触及最好的玩伴之间的相互接触是四川省藏族农区学校猪囊尾蚴感染传播的主要途径,其学校儿童整体社会网络中的"核心人物"、"信息传播者"和"信息枢纽"是预防与控制的关键。更多还原

【Abstract】 Objective To determine the transmission characteristics of Cysticercuscellulose infections from a social network perspective in Tibetan school children in Sichuan.Methods A cluster sampling strategy was adopted to select two primary schools with high level of Cysticercuscellulose infections in the Tibetan agriculture areas of Liangshan prefecture,Sichuan province.All of the students from the selected schools were enrolled in the study.Their social network data,including classroom seating,dormitory roommates,best playmates,and those who shared meals and snacks etc,were collected by trained investigators.Stool and blood samples of the students were collected for parasite detection.The transmission network of Cysticercuscellulose infections and the overall social network of school children were analysed.Results A total of 644 children participated in the study.Taenia solium were found in 6.11% of the stool samples and 13.25% blood samples returned with seropositive.The transmission was centered around the sources of infections:dormitory-clustering in the boarding school and playmate-clustering in the day school.The overall social network analysis revealed "core people"(more relationships),"information disseminators"(closer to other nodes)and"information hubs"(between two nodes)in both schools.ConclusionClose contacts in dormitories and playgrounds are the main sources of transmission of cysticercosis in the Tibetan schools.The"core people""information disseminators"and "information hubs"are critical for the prevention and control of cysticercosis in the future.更多还原