Toll-like receptor 4(TLR4),a member of the TLR receptor family,is highly expressed in colorectal cancers.TLR4 has been proved to be the ligand of many bacterial lipopolysaccharide.TLR4 plays an important role in the growth,invasion,metastasis and immune escape of colorectal tumors by activating TLR4 downstream target molecules and mediating a series of signal transduction pathways after recognizing lipopolysaccharide.At present,the research on the mechanism of occurrence and development of colorectal cancer...
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