【摘要】 目的研究及观察阿托伐他汀钙对急性脑梗死患者神经功能及血管损伤指标的影响。方法将2015-06—2016-06安阳市人民医院收治的66例急性脑梗死患者选为研究对象,66例患者随机分为对照组和观察组各33例,对照组进行常规脑梗死治疗,观察组则在对照组常规治疗的基础上加用阿托伐他汀钙,然后将对照组和观察组治疗前后不同时间的神经功能缺损评分、血浆高迁移率族蛋白b1、神经功能相关指标及血管损伤指标进行比较。结果治疗前2组患者的神经功能缺损评分、血浆高迁移率族蛋白b1、神经功能相关指标及血管损伤指标比较,P>0.05;治疗后不同时间观察组的评分及血浆指标检测结果均显著好于对照组,P<0.05。结论阿托伐他汀钙可有效改善急性脑梗死患者的神经功能及血管损伤指标。更多还原

【Abstract】 Objective To study and observe the influence of atorvastatin calcium for the nerve function and vascular injury indexes of patients with acute cerebral infarction.Methods 66 patients with acute cerebral infarction in our hospital from June2015 to June 2016 were selected as the study object and were randomly divided into control group and observation group with 33 cases in each group,then the control group were treated with routine treatment of acute cerebral infarction,the observation group were treated with atorvastatin calcium on the routine treatment of control group,then the neuralogic function defect score,plasma high mobility group box-1protein,nerve function related indexes and vascular injury related indexes of control group and observation group at different time before and after the treatment were compared.Results The neurologic function defect score,plasma high mobility group box-1protein,neurologic function related indexes and vascular injury related indexes of two groups before the treatment were compared,all P>0.05,while the neural function defect score and plasma detection indexes of observation group were all significantly better than those of control group(P<0.05).Conclusions Atorvastatin calcium can effectively improve the nerve function and vascular injury indexes of patients with acute cerebral infarction.更多还原