Objective To investigate the clinical features,therapeutic effects and adverse reactions of the lung cancer brain metastases with first manifestation of neuropsychiatric symptoms.Methods 42 cases of lung cancer brain metastases in our hospital from June 2007 to Mar 2013 were divided into two groups,the observation group(n=22)received temozolomide combined with radiotherapy therapy,the control group(n=20)received radiotherapy treatment only.The efficacy,adverse reaction and survival rates were compared.Resul...