【摘要】 目的建立生活饮用水及水源水中15种有机污染物残留量的超高效液相色谱-串联质谱检测方法。方法水样经0.22μm滤膜过滤后,Waters ACQUITY UPLC BEH C18色谱柱(2.1 mm×100 mm,1.7μm)分离,以乙腈-0.1%甲酸水溶液为流动相进行梯度洗脱,以多反应监测(MRM)方式正负离子化模式进行检测。结果 15种有机污染物在0.5~10μg/L(除五氯酚、2,4-滴为5.0~100μg/L)的线性范围内,所得的回归方程均呈良好的线性关系,r>0.998。该方法的检出限为0.05~2.0μg/L,平均回收率为85.0%~105.9%,RSD为1.23%~7.12%。结论该方法快速、准确、灵敏度高,适用于生活饮用水及水源水中15种有机污染物残留检测。更多还原

【Abstract】 Objective An Ultra performance liquid chromatography-mass/mass spectrometry method was established for the simultaneous determination of fifteen organic contaminants residue in drinking water and source water. Methods The water samples were filtered by 0.22 μm membrane filter,the chromatography separation was performed on a Waters ACQUITY UPLC BEH C18 column(2.1 mm×100 mm,1.7 μm) by acetonitrile and water(with 0.1% formic acid), as mobile phase, in gradient elution program. MS/MS was performed by electrospray ionization in positive and negative mode with multiple reaction monitoring(MRM) mode. Results The calibration curves showed a good linearity in the range of 0.5-10 μg/L and 5-100 μg/L(2, 4-D and pentachlorophenol),r>0.998. The limits of detection of the method were between 0.05 and 2.0 μg/L.The average recoveries of the method were between 85.0% and 105.9% and relative standard deviation(RSD) were between 1.23% and7.12%. Conclusion The method has been proved to be rapid,accurate,sensitive. The method is suitable for the determination of fifteen organic contaminants residue in drinking water and source water.更多还原