【摘要】 针对我国发酵类制药行业生产过程中产生的菌渣难处理问题,以制药菌渣为研究对象,将制药厂综合污泥为对照,采用热水解(thermal hydrolysis)预处理技术,研究高含固率制药菌渣在170℃,800 000 Pa和30 min水解条件下的处理效果,并进行生物化学产甲烷潜能实验,考察热水解预处理对制药菌渣厌氧消化效率的提高程度。结果表明,VB12菌渣、青霉素菌渣、综合污泥在预处理后,SCOD分别增加了80.00%、-28.57%、275%,TN分别增加了76.98%、-76.53%、93.68%,TP分别增加了101.10%、-81.97%、167.86%。VB12菌渣、青霉素菌渣、综合污泥在厌氧消化后,VS去除率为82.52%、63.76%、61.07%。累计产甲烷量分别提高了258.23%、740.63%、190.75%,可见热水解预处理提高产甲烷性能效果显著。与现有填埋、焚烧处理技术相比,厌氧消化能实现菌渣的资源化处置。为热水解与厌氧消化组合工艺处理制药菌渣在我国制药行业的工程应用提供参考。更多还原

【Abstract】 Treatment of mycelial residue is a bottleneck in fermenting pharmaceutical industry of China. Two kinds of mycelial residue were investigated, with integrated sludge from pharmaceutical wastewater treatment plant as control. Effect of high solid content mycelial residue was studied by thermal hydrolysis with operating conditions of 170 ℃, 800 000 Pa and 30 min. Results showed that SCOD of VB12 mycelial residue, penicillinase mycelial residue and sludge increased by 80.00%,-28.57% and 275%, TN increased by 76.98%,-76.53% and 93.68%,and TP increased by 101.10%,-81.97% and 167.86% after pretreatment, respectively. After anaerobic digestion,VS of VB12 mycelial residue, penicillinase mycelial residue and sludge removed by 82.52%, 63.76% and 61.07%,respectively. The cumulative methane production increased by 258.23%, 740.63% and 190.75%, respectively,which showed that the effect of thermal hydrolysis pretreatment on methane production was remarkable. Compared with the landfill and incineration method, anaerobic digestion can realize the resource disposal of mycelial residue.This study provides a reference of the anaerobic digestion combined with thermal hydrolysis pretreatment to dispose mycelial residue in Chinese pharmaceutical industry for engineering applications.更多还原