【摘要】 在无催化剂、室温条件下由3-环己烯甲酸-3′-环己烯甲酯（简称A）环氧化反应合成3,4-环氧环己基甲酸-3′,4′-环氧环己基甲酯（AOO）。以环境友好的H₂O₂为氧源,1,2-二氯乙烷为溶剂,考察了n（A）∶n（H₂O₂）、反应温度、反应时间、溶剂用量、除水剂用量、缓冲剂用量等对反应的影响。结果表明,以25 mmol的A计,适宜的合成条件,1,2-二氯乙烷16 mL,n（A）∶n（H₂O₂）为1.0∶3.5,A与乙酸酐摩尔比为1∶4,A与无水乙酸钠摩尔比为1.0∶0.5,室温条件下反应2.5 h。在该条件下,经气相监测得A的转化率达99.0%,AOO的产率达90%以上,纯度达99.03%。更多还原

【Abstract】 3,4-epoxycyclohexylmethyl-3′,4′-epoxycyclohexane carboxylate（AOO） was synthesized via the epoxidation of 3-cyclohexenylmethyl-3′-cyclohexene carboxylate（A） under the conditions of catalyst free and room temperature. Environmentally-friendly hydrogen peroxide was used as oxygen source and 1,2-dichloroethane as solvent to observe the effects of the molar ratio of A and H₂O₂,reaction temperature,reaction time,amount of solvent,dehydrating agent and buffer on the reaction. The results show that the optimal synthetic conditions in the presence of A of 25 mmol are as follows:A of 25 mmol,1,2-dichloroethane of 16 mL,the molar ratio of A/H₂O₂,A/acetic anhydride and A/anhydrous sodium acetate are 1.0∶3.5,1∶4,1.0∶0.5 respectively,and reacted at room temperature for 2.5 h. The test results from gas phase monitoring indicate that under these conditions the conversion rate of A is up to 99%,the yield of AOO is beyond 90%,and the purity of the product reaches 99.03%.更多还原