【摘要】 目的探讨和评价应用可调改的下颌前移矫治器治疗阻塞性睡眠呼吸暂停低通气综合征(obstructive sleep apnea and hypopnea syndrome,OSAHS)的疗效。方法对前来求治的已确诊的OSAHS患者14例采用自身前后对照试验,选择戴用改良、方便调改的口腔矫治器,治疗前后带矫治器进行多导睡眠监测(PSG)观察疗效,治疗前后通过问卷调查和嗜睡评分,记录患者的主观感受和症状的变化及不良反应。结果 12例呼吸暂停指数降低了74.1%以上,客观有效率达到85.71%,治疗后呼吸暂停指数(AI)、低通气指数(HI)明显降低(P<0.05),呼吸暂停及低通气指数(AHI)、最长呼吸暂停低时间、最低血氧饱和度(LSa O2)及嗜睡评分变化显著(P<0.01)。戴矫治器后的主要不良反应为初期唾液增多,晨起颞下颌关节和个别牙齿短暂的酸胀不适。结论 12例患者戴用改良可调改的口腔矫治器达到了良好的临床效果,并且该矫治器方便临床操作。长期的效果和不良反应还需进一步观察。更多还原

【Abstract】 Objective To evaluate the clinical effects of improved adjustable oral cavity appliance in treatment of obstructive sleep apnea-hypopnea syndrome( OSAHS). Methods Fourteen patients with OSAHS who were treated by wearing improved adjustable oral cavity appliance were enrolled as subjects. The polysomonography was used to observe the therapeutic effects,moreover,the queationnaire and hypersomnia score were used to observe the changes of subjective symptoms of patients before and after treatment and adverse reactions. Results The AI indexes in 12 patients with OSAHS who wore the improved adjustable oral cavity appliance were decreased by more than 74. 1%,with objective effective rate being 85. 71%,moreover AHI,HI indexes,the longest apnea time,LSSa O2 levels and hypersomnia scores were significantly decreased( P < 0. 01).Conclusion The improved adjustable oral cavity appliance can obtain satisfactory therapeutic effects on OSAHS,with convenient clinical operation,however,it is necessary to observe its long-term effects and adverse reactions.更多还原