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中药活性成分筛选方法研究进展

Research Progress on Screening Methods for Active Components of Traditional Chinese Medicine

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【作者】 毕素侠王莹李大鹏戚进余伯阳

【Author】 BI Su-xia;WANG Ying;LI Da-peng;QI Jin;YU Bo-yang;China Pharmaceutical University,School of Traditional Chinese Pharmacy;

【通讯作者】 余伯阳;

【机构】 中国药科大学中药学院

【摘要】 中药活性成分的筛选对于中药的发展至关重要。目前,已有许多方法技术用于中药活性成分的筛选。本文就近年来国内外对中药活性成分筛选方法的研究进展进行综述,分别介绍了基于活性成分分离鉴定、血清药物化学和血清药理学、代谢组学、分子识别技术、计算机虚拟技术的活性成分筛选方法,以期为中药现代研究提供参考。

【Abstract】 It is very important for the development of traditional Chinese medicine to screen the active components from traditional Chinese medicine. At present,there are many methods and techniques for screening active components of traditional Chinese medicine. This paper reviews the research progress of the active components screening methods for traditional Chinese medicine in recent years. And some active components screening methods based on the separation and identification of active components,serum drug chemistry and serum pharmacology,metabolomics,molecular recognition technology and computer virtualization technology are introduced respectively in this paper. Hoping to provide reference for modern research of traditional Chinese medicine.

【基金】 国家自然科学基金面上项目(81774150);江苏省高校“青蓝工程”资助项目
  • 【文献出处】 海峡药学 ,Strait Pharmaceutical Journal , 编辑部邮箱 ,2018年11期
  • 【分类号】R284
  • 【被引频次】9
  • 【下载频次】1650
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