An automatic aberration compensation method is proposed by combing phase fitting and deep learning in digital holographic microscopy and applications to dynamic observation of living cell morphology.Firstly,in the holography recording plane,the preliminary aberration compensation is implemented by using a digital phase mask,whose quadratic polynomial fitting computation is based on the extraction of reconstructed phase value along central cross line profiles in the field of view.Then,in the holographic imag...
-10001211kinds of living cells,which have different morphological characteristics,with the off-axis digitalholographic microscopy.Furthermore,the proposed method is applied to screen the drug resistance ofendometrial cancer cells.These experimental result