【摘要】 纵向生存数据基本的联合模型都包含一个纵向结果和一个生存结果,该文基于混合效应模型和Cox比例风险模型构建纵向生存数据的标准联合模型和广义联合模型,并利用原发性胆汁性肝硬化(PBC)数据进行建模对比分析,结果表明联合建模结果优于单独生存建模或纵向建模结果,广义联合模型优于标准联合模型.更多还原

【Abstract】 The basic joint model of longitudinal data and survival data contains a longitudinal result and a survival result.This paper constructs the standard joint model and the generalized joint model of longitudinal data and survival data based on the mixed effect model and the Cox proportional hazard model.A comparative analysis of the primary biliary cirrhosis(PBC)data show that joint analysis is better than single analysis,and the generalized joint model is better than the standard joint model.更多还原