【摘要】 目的探讨炎性指标在阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者发生肺栓塞(PE)的预测价值。方法回顾分析2009年1月至2016年6月新疆医科大学第一附属医院收治21例OSAHS合并PE的患者(病例组)资料,按照年龄、性别进行1∶2配对,选取同期在该院确诊为OSAHS的患者42例(对照组),分析2组患者中性粒细胞计数(N)、淋巴细胞计数(L)、中性粒细胞计数/淋巴细胞计数(NLR)等实验室数据,用条件Logistic回归分析各炎性指标与OSAHS患者发生PE的相关性。结果条件Logistic回归多因素分析示,NLR>2.2、白细胞(WBC)<7.0×10~9/L与OSAHS患者发生PE存在显著的相关性,是OSAHS患者并发PE的独立危险因素。结论 NLR可能对OSAHS患者发生PE有一定的预测价值。更多还原

【Abstract】 Objective To identify the predictive value of inflammatory makers in patients who have obstructive sleep apnea-hypopnea syndrome(OSAHS)incident pulmonary embolism.Methods The data of 21 cases of OSAHS with PE treated in the First Affiliated Hospital of Xinjiang Medical University from January2009 to June 2016 were retrospectively analyzed,and the patients were matched according to age and sex with the ratio of 1∶2.42 patients who were diagnosed as OSAHS in that hospital at the same time were selected as the control group.The laboratory data of neutrophils count(N),lymphocyte count(L),neutrophil-lymphocyte ratio(NLR)were analyzed in two groups,and the correlation between each inflammatory index and PE in OSAHS patients was analyzed by conditional Logistic regression.Results Multivariate analysis of conditional Logistic regression showed that there was a significant correlation between NLR>2.2,WBC<7.0×109/L and the occurrence of PE in patients with OSAHS,which was an independent risk factor for PE in OSAHS patients.Conclusion NLR may have a certain predictive value for the occurrence of PE in OSAHS patients.更多还原