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正交实验优选中药复方养阴生肌妇炎栓的提取工艺

Optimization of Extraction Process of YangYin ShengJi Suppository by Orthogonal Experiment

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【作者】 郭敏徐思雨顾万红古秋莉

【Author】 GUO Min;XU Siyu;GU Wanhong;GU Qiuli;Gansu Provincial Academy of Chinese Medicine;Gansu Provincial Hospital of Traditional Chinese Medicine;

【机构】 甘肃省中医药研究院甘肃省中医院

【摘要】 目的:优选中药复方养阴生肌妇炎栓的最佳提取工艺。方法:采用正交实验法,以乙醇浓度、提取时间和料液比为因素,以提取物中龙胆苦苷的含量和浸膏得率为考察指标,根据L9(34)正交表进行实验。结果:中药复方养阴生肌妇炎栓的最佳提取工艺为:乙醇浓度80%,提取时间5.0小时,料液比为8:1。结论:乙醇浓度和提取时间对龙胆苦苷的含量和浸膏率影响较大;该工艺方法简单、实用,具有可操作性。

【Abstract】 Objective: To choose the optimal extraction process of YangYin ShengJi suppository. Methods:The experiment was performed according to L9 (34) orthogonal list by using orthogonal experiment, taking ethanol concentration, extraction time and solid-liquid ratio as the factors, and the contents of gentiamarin and extraction ratio in the extractive as the indexes. Results: The optimal extraction process of YangYin ShengJi suppository was:ethanol concentration 80%, extraction time 5.0 hours, solid-liquid ratio 8:1. Conclusion: Ethanol concentration and extraction time present greater influence to the contents of gentiamarin and extraction ratio, the technique is simple, practical and operable.

【基金】 甘肃省自然科学基金(编号1606RJ A149)
  • 【文献出处】 西部中医药 ,Western Journal of Traditional Chinese Medicine , 编辑部邮箱 ,2018年03期
  • 【分类号】R283.6
  • 【被引频次】1
  • 【下载频次】233
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