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抗磷脂抗体对孕产妇及新生儿的影响

Effect of antiphospholipid antibody on maternal and neonates

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【作者】 罗兆芹杨炜尹秀琴

【Author】 LUO Zhaoqin;YANG Wei;YIN Xiuqin;Dept.of Obstetrics,the People’s Hospital of Guilin;

【机构】 桂林市人民医院产科

【摘要】 目的:探讨抗磷脂抗体对孕产妇和新生儿的影响。方法:将581例有病理妊娠史和有病理妊娠的孕妇作为观察组,500例无妊娠合并症的孕妇作为对照组,两组进行各项指标对比分析。结果:抗磷脂抗体阳性率在观察组中显著增高,以子痫前期组阳性率最高;观察组中,抗磷脂抗体阳性的孕妇早产率和新生儿窒息率明显高于抗磷脂抗体阴性的孕妇,差异具有统计学意义(P<0.05)。结论:检测抗磷脂抗体可以对高危孕妇妊娠结局进行预防和控制。

【Abstract】 Objective: To explore the effect of antiphospholipid antibody on maternal and newborns.Methods: 581 patients having pathological pregnancy history and pregnant women with pathological pregnancy were treated as the observation group, while 500 pregnant women with no pregnancy complications were selected as the control group. The various indexes in both groups were compared and analyzed. Results: The positive rate of anti-phospholipid antibody was significantly increased in the observation group,with the highest positive rate in the preeclampsia group. In the observation group,the preterm premature birth rate and neonatal asphyxia rate were significantly higher in pregnant women with positive anti-phospholipid antibody than those in pregnant women with negative anti-phospholipid antibody.The difference was statistically significant( P < 0. 05). Conclusion: For high-risk pregnant women,the detection of anti-phospholipid antibodies can prevent and control the adverse pregnancy outcomes.

【关键词】 抗磷脂肮体孕产妇新生儿
【Key words】 antiphospholipid antibodiespregnant womanneonate
【基金】 桂林市科学研究与技术开发计划资助项目(20150403-1-3)
  • 【文献出处】 华夏医学 ,Acta Medicinae Sinica , 编辑部邮箱 ,2018年03期
  • 【分类号】R714
  • 【被引频次】6
  • 【下载频次】161
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