Objective To provide multiple choices for cells for in vitro studies of osteoarthritis by comparing the effect of Interleukin-1β(IL-1β) treatment on proliferation activity, inflammatory factors and the expression of inflammatory pathways in primary chondrocytes and SW1353 chondrosarcoma cell lines. Methods Immunocytochemical staining and toluidine blue staining were used to detect type II collagen and proteoglycan, respectively, and to identify whether the cultured primary cells were chondrocytes. cck-8 ass...