Tumor is a most deadly killer of humans. The low therapeutic efficiency and significant side effects caused by antitumor drugs are the main problems for tumor treatment currently. The use of tumor targeting drug carrier can greatly improve the therapeutic effect and reduce the side effects of antitumor drugs. However, the complex microenvironment of tumor(such as tumor progression, the expression level of related enzymes, and precise location of tumor cells) and individual difference among cancer patients(l...