Herein we report the syntheses of a GSH-responsive peptide probe NI-GFFKESSRGD which was conjugated with an aggregation-induced-emission dye NI-COOH( AIEgen). GSH reduced the disulfide bond of the peptide and cleaved the hydrophilic moiety RGD,resulting in the self-assembly of peptide and formation of supramolecular hydrogels. When the GSH concentration was in the range of50-600 μmol/L,the fluorescence intensity of peptide was in good linear relationship with the GSH concentration,thereby leading to the acc...
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