【摘要】 目的:评估国产药涂球囊法治疗下肢动脉粥样硬化闭塞症的安全性及有效性。方法:回顾性分析2017年7月-2017年12月在本院接受国产紫杉醇药涂球囊治疗的22例股动脉-腘动脉粥样硬化闭塞症患者的病例资料,对所有患者在术后1、3和6个月时进行随访,分析一期血管通畅率、Rutherford分级、患者再次入院治疗以及症状缓解情况等。结果:入组患者术前和术后一个月时的踝肱指数(ABI)分别为0.39±0.18和0.69±0.21;术前及术后6个月时的病变血管Rutherford分级分别为3.72±1.24和2.05±1.07。所有患者的主要临床症状在术后逐渐改善,术后6个月时的一期通畅率为100%,随访时间内出现不良反应、截肢以及死亡病例数均为0。结论:国产紫杉醇药涂球囊法治疗下肢动脉硬化闭塞症具有良好的临床疗效及可靠的安全性。更多还原

【Abstract】 Objective:To evaluate the safety and efficacy of domestic paclitaxel coated balloon in the treatment of atherosclerotic occlusive disease of lower extremities.Methods:Twenty-two patients with femoral-popliteal atherosclerotic obliterans receiving paclitaxel coated balloon treatment in our hospital from July 2017 to December 2017 were collected and their clinical data were analyzed retrospectively.The patients were followed up at 1,3,and 6months after the operation.The main endpoints were primary patency rate,Rutherford grade,readmission and symptom relief at 6months after operation.Results:Ankle brachial index(ABI)was 0.39±0.18 before operation,and 0.69±0.21 at one month follow-up.Rutherford grading was 3.72±1.24 before operation,and 2.05±1.07 at six-month follow-up.The main clinical symptoms of all the patients were gradually relieved,and the patency rate was 100%at 6-month follow-up.The number of adverse reactions,amputations and deaths was 0during the follow-up period.Conclusion:Domestic paclitaxel coated balloon is of good clinical efficacy and safe in the treatment of arteriosclerosis obliterans in the lower extremities.更多还原