【摘要】 目的了解湖北省儿童第二类疫苗接种情况,为制定有效防控第二类疫苗针对疾病的措施提供参考。方法从中国免疫规划信息管理系统(National Immunization Program Information System,NIPIS)提取湖北省2010—2016年报告的第二类疫苗接种数据,并从湖北省儿童预防接种信息管理系统(Children Immunization Information Management System,CIIMS)中通过接种个案统计2010—2016年湖北省第二类疫苗接种数据,采用描述流行病学方法进行分析。结果 2010—2016年第二类疫苗在NIPIS中共报告接种20 762 193剂次,年平均接种2 966 028剂次,在CIIMS中统计共接种22 640 938剂次,年平均接种3 234 420剂次。剔除两个系统中各年新增加报告的疫苗品种,CIIMS统计的接种剂次数比NIPIS报告的接种剂次数高4.32%。CIIMS统计2010—2016年湖北省第二类疫苗累计人均接种4.55剂次。对报告剂次数最多的3种疫苗分析全程接种率,水痘减毒活疫苗(Varicella Attenuated Live Vaccine,Var V)全程接种率最高(55.92%),含b型流感嗜血杆菌(Haemophilus Influenza Type b Polysaccharide Conjugate Vaccine,Hib)成分疫苗第2(19.63%),流感疫苗(Influenza Vaccine,Inf V)第3(8.21%)。结论湖北省儿童第二类疫苗人均接种剂次数不高,部分疫苗针对传染病暴发原因是疫苗接种率低。应重视第二类疫苗的预防接种服务和管理,提高接种率;应建立有效的第二类疫苗监测系统,更加有效地开展第二类疫苗针对疾病的防控工作。更多还原

【Abstract】 Objective In order to acknowledge the category Ⅱ vaccine application status,to provide scientific evidence for making effective disease control strategies with the category Ⅱvaccine. Methods Data of the category Ⅱ vaccine utilization in Hubei in2010-2016 were derived from NIPIS( National Immunization Program Information System) and vaccination case data were collect from CIIMS( Children Immunization Information Management System). Descriptive epidemiological analysis was applied. Results There were 20 762 193 of the category Ⅱ vaccine doses taken according to the NIPIS report in 2010-2016. Annual average was 2 966 028 doses. There were 22 640 938 doses recorded in the CIIMS. Annual average was 3 234 420 doses. Except the new report of vaccine added in the two system during those years,doses used reported by CIIMS was 4. 32% higher than NIPIS. The average doses reported by CIIMS is 4. 55 of Hubei in 2010-2016. The whole coverage rates of the highest three vaccines were analyzed. There were 55. 92%of Varicella Attenuated Live Vaccine( Var V),19. 63% of Haemophilus Influenza Type b Polysaccharide Conjugate Vaccine( Hib) and8. 21% of Influenza Vaccine( Inf V). Conclusion The average doses was low for category Ⅱ vaccine application in children of Hubei. Ourkreak of some vaccine preventable infectious diseases were still due to low vaccination rate. We should take immunization service and administration seriously,improve vaccination rates. There should be an effective category Ⅱ vaccine surveillance system to make the diseases prevention work more effective.更多还原