【摘要】 目的:评价热毒宁注射液在儿科超说明书用药情况,为儿童安全合理应用热毒宁注射液提供参考。方法:抽取我院儿科2016年使用热毒宁注射液的出院病历,对患儿的基本情况、给药剂量、用药频次、配制浓度、用药疗程等信息进行统计分析。结果:超说明书用药患儿年龄:<3岁占11.07%,3~5岁占37.37%,6~10岁占48.10%,11~13岁占3.46%;超说明书用药类型:超疗程用药占69.81%,单次给药剂量低于治疗剂量占22.01%,配制浓度过低占7.55%。结论:热毒宁注射液在儿科存在超说明书用药情况,应加强临床应用管理,促进其规范使用,保障患儿用药安全。更多还原

【Abstract】 Objective: To evaluate the off-label drug use of Reduning injection in pediatric,so as to provide reference for the rational use and clinical management of Reduning injection on children. Methods: Discharged medical records with application of Reduning injection in pediatric were extracted and analyzed in terms of patients ’ general information,dosage,frequency of administration,formulation concentration,treatment course. Results: Of the child patients’ applied with Reduning injection,11. 07% were < 3 years old,37. 37% were aged between 3 to 5,48. 10% were aged between 6 to 10,3. 46% were aged between 11 to 13; the types of off-label drug use included 69. 81% of over-course of treatment,22. 01% of lower administration dose than therapeutic dose,and 7. 55% of over lowering formulation concentration. Conclusion: Off-label drug use of Reduning injection exists in pediatric,which should be given strengthened management,with its standardized use promoted and the safety of children’s medication ensured.更多还原