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一例犬外周神经鞘瘤的诊断

A Case Diagnosis of Peripheral Schwannoma in a Dog

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【作者】 文兆海闫书平胡远毛丽萍程瑶陈凯云翟少华简子健

【Author】 WEN Zhao-hai;YAN Shu-ping;HU Yuan;MAO Li-ping;CHENG Yao;CHEN Kai-yun;ZHAI Shao-hua;JIAN Zi-jian;College of Veterinary Medicine,Xinjiang Agricultural University;

【机构】 新疆农业大学动物医学院

【摘要】 为了对一例患犬腕部肿物进行诊断,通过病史调查、触诊、直接数字化X射线摄影系统(DR)、血常规、生化指标等一系列检查后,临床上诊断为肿瘤,对肿瘤组织采样,经40g/L的甲醛固定后送新疆农业大学动物医学院病理诊断实验室检查。眼观,该肿物呈结节状,表面不平整,外有包膜包裹,大小为4cm×3.7cm×2.1cm。显微镜下观察,肿瘤组织呈现两种形态(Antoni A型和Antoni B型),为神经鞘细胞的增生,未见核分裂象。Antoni A肿瘤细胞型以纺锤形细胞增生为主,排列紧密,可呈束状、波浪状、栅栏状排列。Antoni B型的肿瘤细胞较少,呈纺锤形,排列稀疏,间质发生黏液样变性。经病理组织学观察,确诊为神经鞘瘤,且为混合型。

【Abstract】 In order to diagnose a dog with a goitre in the wrist,medical history survey,palpation,direct digital X ray radiography system(DR),blood routine,biochemistry were performed to conform the canine schwannoma.The biopsy sample from the mass was fixed by 100 g/L formaldehyde and examined with histological analysis in pathology laboratory of Xinjiang Agricultural University.Visual observations showed that the nodular mass with uneven surface was wrapped by capsule,4 cm×3.7 cm×2.1 cm in size.Microscopically,Schwann cells arranged in the characteristic patterns referred to as Antoni A and B,and no further mitotic activity was observed.Histologically,Antoni type A showed the characteristics of schwannoma mainly composed of predominantly spindle cells.The cells have a wavy,buckled appearnce and closely bunched together.There are a few tumor cells in Antoni type B.Antoni type B cells are arranged in small interwoven bundles with intervening fibrous and mucinous stroma.Based on these characteristics,the case was diagnosed as schwannoma with mixed types.

【关键词】 神经鞘瘤病理组织学肿瘤细胞
【Key words】 dogSchwannomahistopathologytumor cell
【基金】 国家自然科学基金项目(31360623)
  • 【文献出处】 动物医学进展 ,Progress in Veterinary Medicine , 编辑部邮箱 ,2018年08期
  • 【分类号】S858.292
  • 【下载频次】83
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