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精细个体化131I治疗Grave’s病合并胸腺增生的疗效观察

Effect of Fine Individualized 131I for Treatment of Grave’s Disease Complicated with Thymic Hyperplasia

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【作者】 李尧梅焦小玲周朋王朋李加宁季志文

【Author】 LI Yaomei;JIAO Xiaoling;ZHOU Peng;WANG Peng;LI Jianing;JI Zhiwen;The Mine Hospital of Xuzhou;

【机构】 徐州市矿山医院核医学科

【摘要】 目的探讨精细个体化131I治疗Grave’s病合并胸腺增生患者的疗效。方法回顾2013年至2017年间7例经过精细个体化131I治疗的Grave’s病合并胸腺增生病例,治疗后半年随访甲状腺功能及胸腺大小的变化。结果 7例Grave’s病合并胸腺增生患者经精细个体化131I治疗后,5例甲亢完全缓解,1例部分缓解,1例甲减;7例增生的胸腺组织均显著缩小(前后径×左右径:13.3±2.47 vs.7.36±1.39,P <0.05)。结论精细个体化131I治疗Grave’s病合并胸腺增生疗效显著,可缓解甲亢症状,有效控制胸腺增生。

【Abstract】 Objective To explore the efficacy of fine individualized 131I in the treatment of Grave’s disease complicated with thymic hyperplasia. Methods From 2013 to 2017,7 cases of thymic hyperplasia complicated with thymic hyperplasiatreated by fine individualized 131I treatment were reviewed. The changes of thyroid function and the size of thymus were compared after 6-month treatment. Results Seven patients with Grave’s disease and thymic hyperplasia were treated with 131I,5 patients were completely relieved,1 patient was partially relieved and 1 patient was hypothyroidism. The thymic tissues of 7 cases were significantly reduced(anteroposterior diameter×left and right diameter:13.3±2.47 vs. 7.36±1.39,P<0.05). Conclusion Grave’s disease combined with thymic hyperplasia has a significant therapeutic effect,which could alleviate hyperthyroidism and effectively control thymic hyperplasia.

【关键词】 131I治疗Grave’s病胸腺增生
【Key words】 131I Therapygrave’s diseasethymic hyperplasia
  • 【分类号】R581.1;R583
  • 【下载频次】54
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