This article employs the OAG(Official Airline Guide) flight schedule data of 2016 to analyze the spatial pattern and classification of multi-airport regions. The results indicate that: besides European countries and the United States, China, Japan, Thailand, and Brazil occupies important positions in the construction of multi-airport regions in the world. Multi-airport regions in Southern Europe, Australia, New Zealand, and West Asia are polarized and lack of secondary airports. The layout of airports in th...