Objective To review the researches of risk factors influencing the quality of life in leprosy patients and describe their progress. Methods The related literatures at home and abroad in recent years were reviewed and summarized. Results The factors influencing the quality of life of leprosy patients were respectively personal factors(sex, age, education background, economic income and the state of illness), factors of disease(type of leprosy, diagnostic delay, reaction of leprosy, neuropathic pain and disab...