【摘要】 目的:文献分析慢性湿疹临床证候的脏腑传变。方法:检索中国知网数据库,纳入1990年至2015年(25年)慢性湿疹文献;依据脏腑辨证,确定患病人群的病机定位;遵循五行生克,确定湿疹病程脏腑定位的传变规律。结果:1 311例湿疹患者的脏腑定位为肝(35.69%),脾(25.25%),心(22.12%),肾(13.80%),肺(3.13%)。结合患者体质特征,提示湿疹发病为"先天肾虚与后天脾虚"双驱动;即湿疹立法"温肾阳治本,渗脾湿治标",肝阴虚为桥联本标的常见表象,以佐药治之。结论:遵循脏腑传变,慢性湿疹病机源于肾虚,症见脾湿,联在肝阴虚;传变动力是立法遣药的客观依据。更多还原

【Abstract】 Objective: To analyze relevant literatures on the zang-fu viscera variable regularity of clinical syndromes of chronic eczema. Methods: The China knowledge network database(CNKI) was searched, and the literatures on chronic eczema from 1990 to 2015 were included. The pathogenesis localizations of patients were determined, based on the syndrome differentiation of zang-fu viscera. The variable regularity of zang-fu viscera localizations of chronic eczema progress were determined, based on the theory of mutual generation and restriction of five phases. Results: The 1 311 cases of chronic eczema were included. The percentages of zang-fu viscera locations were distributed as follows: liver(35.69%), spleen(25.25%), heart(22.12%), kidney(13.80%), and lung(3.13%). Combining with the patients’ allergic constitution, it was suggested that the pathogenesis of chronic eczema was both congenital kidney deficiency and acquired spleen deficiency. Namely, the therapeutic rule of chronic eczema was ‘warming kidney-yang for treating essence, eliminating spleen dampness for treating symptoms’. Liver-yin deficiency was common manifestation of bridging essence and symptoms, and it was treated with assistant drugs. Conclusion: Following the variable regularity of zang-fu viscera, the pathogenesis of chronic eczema is kidney deficiency, spleen dampness can be seen in its symptoms, and its bridge is liver-yin deficiency. Its variable power is its objective evidences of determining the therapeutic rules and medication.更多还原