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膝关节镜治疗骨质疏松性胫骨平台骨折前后患者血清中BALP、TRAP-5b及PICP水平的变化研究

The Changes of Serum Levels of BALP,TRAP-5b and PICP in Patients with Osteoporotic Tibial Plateau Fractures Before and After Knee Arthroscopy

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【作者】 顾宝荣王晓东刘志祥李宏斌

【Author】 GU Bao-rong;WANG Xiao-dong;LIU Zhi-xiang;LI Hong-bin;Department of Orthopedics,the Third People’s Hospital of Nantong;

【通讯作者】 刘志祥;

【机构】 南通市第三人民医院骨科

【摘要】 目的研究经过膝关节镜治疗的骨质疏松性胫骨平台骨折患者血清中血清骨碱性磷酸酶(bone alkaline phophatase,BALP)抗酒石酸酸性磷酸酶-5b(tarte-resistant acid phosphatase,TRAP-5b)及Ⅰ型前胶原C-端肽(tyspeⅠprocollagen C peptide,PICP)水平的变化。方法选取骨质疏松性胫骨平台骨折患者100例,通过酶联免疫吸附试验(ELISA)检测膝关节镜治疗骨质疏松性胫骨平台前后患者血清中BALP、TRAP-5b及PICP水平。结果骨质疏松性胫骨平台骨折患者经过膝关节镜治疗后血清中BALP、TRAP-5b及PICP水平显著高于治疗前血清中的BALP、TRAP-5b及PICP水平,差异具有统计学意义(P<0.05)。结论膝关节镜治疗能促进骨细胞的活性和代谢,进而促进骨的形成,值得临床推广。

【Abstract】 Objective To study the changes of BALP,TRAP-5 b and PICP in serum for osteoporotic tibial plateau fractures patients,who are treated with knee arthroscopy. Methods The levels of BALP,TRAP-Sb and PICP were measured by Elisa in 100 patients with osteoporotic tibial plateau fractures. Results After the treatment,the levels of BALP,TRAP-5 b and PICP in patients were significantly decreased compared with the pre-treatment state(P < 0. 05). Conclusion The treatment of knee mirror can promote the activity and metabolism of bone cells and promote the bone formation,which is worthy of clinical promotion.

  • 【文献出处】 标记免疫分析与临床 ,Labeled Immunoassays and Clinical Medicine , 编辑部邮箱 ,2018年12期
  • 【分类号】R687.3;R580
  • 【被引频次】7
  • 【下载频次】65
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