【摘要】 目的探讨图像引导放疗(IGRT)在肺部恶性肿瘤中的应用价值。方法回顾性分析44例肺部恶性肿瘤患者的临床资料,所有患者采用热塑体模固定,每天行IGRT,根据锥形束CT图像与计划CT图像相匹配,获得患者左右(x)、头脚(y)、前后(z)3个方向的线性误差和旋转误差,并对误差进行校正,分析校正前后摆位误差的变化。结果校正后x、y、z轴上的平均摆位误差分别为(-0.02±0.20)、(0.04±0.21)、(-0.01±0.11)cm,均低于校正前,差异均有统计学意义(P﹤0.05);校正前与校正后旋转x、y、z轴上的平均摆位误差比较,差异均无统计学意义(P﹥0.05);校正后x、y、z轴上的摆位外扩边界值(MPTV)分别较校正前减少2.80、7.16、4.78 mm。结论 IGRT可明显减小肺部恶性肿瘤患者放疗时的摆位误差,缩小MPTV,提高放疗的精确性。更多还原

【Abstract】 Objective To explore the value of image-guided radiotherapy(IGRT) in the treatment for lung malignant tumor. Method 44 patients with lung malignant tumor were retrospectively analyzed, all patients were administered with thermoplastic fixation, and treated with daily IGRT, the conical beam CT image were matched with the planned CT image, and then the linear error and rotation error of the 3 axes of left and right(x), head and foot(y), anterior and posterior(z) were obtained and corrected to analyze the change of the positioning error before and after correction. Result The mean positioning error of x, y and z axes were(-0.02 ± 0.20),(0.04 ± 0.21) and(-0.01 ± 0.11) cm after correction, which were lower compared with that before correction, the differences were statistically significant(P<0.05); there was no significant difference between the mean rotation error on x, y and z axes before and after correction(P>0.05); after correction, the expanding margin value(MPTV) of the x, y and z axes decreased 2.80, 7.16 and 4.78 mm compared with those before correction. Conclusion The application of IGRT can significantly reduce the radiotherapy positioning error in patients with lung malignant tumor, minimizing the MPTV, and improving the accuracy of radiotherapy.更多还原