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硫酸氢氯吡格雷联合血栓通治疗急性脑梗塞临床观察

Clinical Observation on Acute Cerebral Infarction Treated with Clopidogrel Hydrochloride and Xueshuantong

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【作者】 但德胜薛敬明

【Author】 DAN De-sheng;XUE Jing-ming;Huoshan County Hospital;

【机构】 霍山县医院神经内科

【摘要】 目的:探讨急性脑梗塞患者应用硫酸氢氯吡格雷联合血栓通治疗的效果。方法:将收治的60例急性脑梗塞患者随机分为对照组、治疗组,每组30例。对照组给予调脂、抗血小板治疗,治疗组在对照组治疗基础上联合硫酸氢氯吡格雷、血栓通治疗。结果:治疗后,治疗组总有效率、NIHSS评分、梗塞区脑血流量均明显优于对照组,差异有统计学意义(P<0.05);两组不良反应差异无统计学意义(P>0.05)。结论:硫酸氢氯吡格雷、血栓通治疗联合治疗急性脑梗塞的疗效提出,能增加梗死部位血流量,挽救濒死神经细胞,缩小暗区,不良反应少,疗效安全可靠。

【Abstract】 Objective:To observe the clinical effect of combined treatment of clopidogrel bisulfide and thrombosis in patients with acute cerebral infarction.Methods:Sixty patients with acute cerebral infarction who were admitted to Hospital were randomly divided into control group and treatment group, with 30 cases in each group. The control group was given lipid-regulating and anti-platelet therapy, and the treatment group was combined with clopidogrel hydrogen sulfate and thrombosis-pass treatment on the basis of the control group.Results:After treatment, the total effective rate, NIHSS score and cerebral blood flow in the infarcted area were significantly better in the treatment group than in the control group(P<0.05). There was no significant difference between the two groups(P>0.05). Conclusion:The therapeutic effect of clopidogrel bisulfide and thrombosis combined therapy for acute cerebral infarction suggests that it can increase blood flow in infarct area, save the dead neurons, reduce the dark area, and have fewer adverse reactions. The curative effect is safe and reliable.

  • 【文献出处】 安徽卫生职业技术学院学报 ,Journal of Anhui Health Vocational & Technical College , 编辑部邮箱 ,2018年03期
  • 【分类号】R743.33
  • 【被引频次】4
  • 【下载频次】50
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