With Huaiyuan pomegranate seed as raw material,pomegranate seed oil was extracted by supercritical CO_2.On the basis of single factor experiment,four extraction parameters including extraction pressure,extraction temperature,extraction time and grinding degree were selected as independent variables,pomegranate seed oil yield was response value,and supercritical CO_2 extraction conditions of Huaiyuan pomegranate seed oil were optimized by response surface methodology.The physicochemical indexes and antioxida...