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颈项透明层筛查胎儿染色体异常的临床价值
Clinical value of nuchal translucency in screening fetal chromosomal abnormalities
【摘要】 目的评估胎儿颈项透明层筛查胎儿染色体异常的临床价值。方法对1053名孕11-13+6周行胎儿颈项透明层测量与妊娠结局相对照,比较不同检查方案的敏感性。结果 1053例孕妇,共检出7例染色体异常的胎儿,颈项透明层敏感度是71.43%,特异度分别为95.85%。结论胎儿颈项透明层对胎儿染色体异常及其他畸形的筛查有意义。
【Abstract】 Objective:To evaluate the clinical value of fetal nuchal translucency in screening fetal chromosomal abnormalities. Methods:1053 cases of 11-13+6 weeks of pregnancy were compared with the outcome of pregnancy,and compared the sensitivity of different protocols. Results:In 1053 cases of pregnant women,a total of 7 cases of abnormal chromosome were detected. The sensitivity of nuchal translucency was about 71.43%,and the specificity was about 95.85%. Conclusion:Fetal nuchal translucency is of significance in screening fetal chromosomal abnormalities and other abnormalities.
【Key words】 Nuchal translucency; Fetal; Chromosomal abnormality; Prenatal screening;
- 【文献出处】 中国优生与遗传杂志 ,Chinese Journal of Birth Health & Heredity , 编辑部邮箱 ,2017年08期
- 【分类号】R440;R714.5
- 【被引频次】1
- 【下载频次】45