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颈项透明层筛查胎儿染色体异常的临床价值

Clinical value of nuchal translucency in screening fetal chromosomal abnormalities

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【作者】 朱启英吴努尔李珊

【Author】 ZHU Qi-ying;WU Nu-er;LI Shan;The First Affiliated Hospital of Xinjiang Medical University Medical Center at the Production Department;

【机构】 新疆医科大学第一附属医院母胎医学中心产一科

【摘要】 目的评估胎儿颈项透明层筛查胎儿染色体异常的临床价值。方法对1053名孕11-13+6周行胎儿颈项透明层测量与妊娠结局相对照,比较不同检查方案的敏感性。结果 1053例孕妇,共检出7例染色体异常的胎儿,颈项透明层敏感度是71.43%,特异度分别为95.85%。结论胎儿颈项透明层对胎儿染色体异常及其他畸形的筛查有意义。

【Abstract】 Objective:To evaluate the clinical value of fetal nuchal translucency in screening fetal chromosomal abnormalities. Methods:1053 cases of 11-13+6 weeks of pregnancy were compared with the outcome of pregnancy,and compared the sensitivity of different protocols. Results:In 1053 cases of pregnant women,a total of 7 cases of abnormal chromosome were detected. The sensitivity of nuchal translucency was about 71.43%,and the specificity was about 95.85%. Conclusion:Fetal nuchal translucency is of significance in screening fetal chromosomal abnormalities and other abnormalities.

  • 【文献出处】 中国优生与遗传杂志 ,Chinese Journal of Birth Health & Heredity , 编辑部邮箱 ,2017年08期
  • 【分类号】R440;R714.5
  • 【被引频次】1
  • 【下载频次】45
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