【摘要】 目的探讨男性原发不育与染色体异常的关系。方法对来自广东省计划生育专科医院不育门诊的2656例男性原发不育患者进行染色体核型分析。结果在这2656例男性患者中,共检出异常核型417例,染色体异常发生率为15.70%(417/2656)。其中性染色体数目异常339例,占总异常的81.29%(339/417),性染色体结构异常28例,占6.71%(28/417),常染色体数目异常2例,占0.48%(2/417),常染色体结构异常44例,占10.55%(44/417)。对染色体异常患者进行精液常规分析。结论染色体异常是造成男性原发不育的重要遗传因素,染色体检查对男性原发不育患者的诊断与治疗有重要意义。更多还原

【Abstract】 Objective:To investigate the relationship between chromosomal abnormalities and male primary sterility. Methods:Chromosome analysis was performed in 2656 male patients with primary sterility from Family Planning Special Hospital of Gangdong. Results:417 cases of chromosomal abnormalities were checked out from 2656 total cases and the abnormal rate was 15.70%. The number of abnormal sex chromosomes number is 339 cases,accounting for 81.29% of the total abnormal chromosomes,the number of abnormal sex chromosomes structure is 28 cases,accounting for 6.71%,the number of abnormal euchromosomes number is 2 cases,accounting for 0.48%,the number of abnormal euchromosomes structure is 44 cases,accounting for 10.55%. The routine semen analysis was performed in patients with abnormal chromosome. Conclution:The chromosomal anomalies are important inheritance factor for male primary sterility. Chromosome analysis was very important for diagnosis and treatment of male patients with primary sterility.更多还原