【摘要】 目的探讨胃腔充盈程度对进展期胃癌肿瘤厚度测量的影响及肿瘤厚度测量的临床意义。方法收集进展期胃癌患者38例(初诊21例,非手术治疗后复诊17例),采用低张气体充盈法,分别于平扫(充盈前)及增强静脉期(充盈后)轴位图像测量并比较胃腔充盈前、后各分区正常胃壁及肿瘤的厚度。同一观察者于1个月后进行再次测量,比较2次测量的一致性。结果各分区正常胃壁充盈前、后厚度的差异有统计学意义(P均<0.001),胃体大弯厚度变化最大。胃腔充盈前后初诊胃癌肿瘤厚度差异无统计学意义(P均>0.05),而复诊胃癌肿瘤厚度差异有统计学意义(P均<0.05)。同一观察者2次测量的肿瘤厚度一致性好。结论初诊进展期胃癌肿瘤厚度相对固定,可作为CT检查的测量指标,复诊时应尽量使胃腔充盈程度与治疗前一致,以准确评价治疗效果。更多还原

【Abstract】 Objective To investigate the effect of gastric filling degree on the thickness of advanced gastric carcinoma and the clinical value of the thickness measured by CT.Methods Totally 38 patients with advanced gastric carcinoma were enrolled and 21 patients were newly diagnosed,17 patients were reexamination after non-surgical treatments.The stomach cavity was filled with oral gas-producing powder.The plain scanning(before filling)and enhanced scanning in venous phase(after filling)were performed.The thickness of the normal gastric wall and gastric carcinoma before and after filling were measured on axial images,and the differences were compared.The patients were measured again one month later by the same investigator,and the consistency between the twice measurements was evaluated.Results Before and after filling,the normal gastric wall thickness of each regions was significantly different(all P<0.001),and the change was greatest at the region of greater curvature.Carcinoma thickness was similar in newly diagnosed patients(P<0.05),but significantly different in patients for reexamination(P<0.05).The twice measurements had a good consistency.Conclusion The thickness of gastric carcinoma can be considered as a baseline measurement indicator in newly diagnosed patients.It is critical to maintaining a similar gastric filling degree during reexamination,which is helpful to evaluate the efficacy of treatment accurately.更多还原