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正交试验法优选和胃抗逆丸制备工艺

Optimization of Preparation Process of Hewei Kangni Decoction by Orthogonal Test

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【作者】 刘洪伟谢微杳

【Author】 LIU Hongwei;XIE Weiyao;Chongqing Hospital of Traditional Chinese Medicine;

【机构】 重庆市中医院

【摘要】 目的优选并确立和胃抗逆丸的最佳制备工艺。方法以和胃抗逆丸溶散时间为考察指标,采用正交试验法对丸剂制备过程中的药材粉碎度(A)、乙醇浓度(B)、干燥温度(C)、干燥时间(D)4个因素进行优选研究。结果和胃抗逆丸的最佳制备工艺为:药材粉碎成60目细粉,用60%的乙醇泛丸,制成的丸剂在70℃干燥6 h。结论该制备工艺科学合理,溶散时限短,为制备和胃抗逆丸的最佳工艺。

【Abstract】 Objective: To optimize and establish the best preparation process of Hewei Kangni Decoction.Methods: The dissolution time Hewei Kangni Decoction of was used as the index. The orthogonal test was used to optimize the 4 factors,including the degree of comminution(A),the concentration of ethanol(B),the drying temperature(C) and the drying time(D). Results: The best preparation process of Hewei Kangni Decoction was that the medicinal material was crushed into 60 mesh powder,and pills made from 60% ethanol pellets were dried for six hours under 70 ℃. Conclusion: The preparation process is scientific and reasonable,and the dissolution time is short. It is the best process for Hewei Kangni Decoction.

【基金】 重庆市江北区科技计划资助项目(20120211)
  • 【文献出处】 中国中医急症 ,Journal of Emergency in Traditional Chinese Medicine , 编辑部邮箱 ,2017年07期
  • 【分类号】R283.6
  • 【被引频次】1
  • 【下载频次】155
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