【摘要】 目的了解北京市大兴区食源性疾病主要致病菌分布及其变化趋势,提高食源性疾病暴发的早期识别、预警与防控能力。方法对在大兴区3家二级医院就诊的腹泻患者进行流行病学调查,采集未使用抗生素患者的粪便标本,进行霍乱弧菌、痢疾杆菌(志贺菌)、副溶血弧菌、沙门菌和5种致泻性大肠埃希菌等细菌的分离培养和鉴定。结果食源性疾病的发生主要集中在2、3季度,各哨点医院肠道门诊就诊量峰值出现在3季度,4年间采集1 773份腹泻患者粪便标本,共检出食源性致病微生物231株,总检出率13.03%,2015年阳性率最高,为22.32%。4年中检出沙门菌114株(49.35%)、肠致病性大肠杆菌41株(17.75%)、志贺菌27株(11.68%)、副溶血弧菌12株(5.19%)、其他肠道病原菌17株(7.36%)、诺如病毒20株(8.66%)。食源性疾病患者主要集中在0~<7岁及20~<40岁2个年龄组,分别占监测人数的32.77%和34.69%;男女性别比为1.37∶1,男女之间差异无统计学意义(P>0.05)。结论大兴区食源性疾病发病主要集中在2、3季度,感染患者主要集中在0~<7岁及20~<40岁年龄组,病原微生物种类繁多,以沙门菌为主,应继续加强监测工作。更多还原

【Abstract】 [Objective]To understand the distribution of major pathogens and their tendency to change in Daxing District of Beijing City,and improve the early identification,early warning and prevention and control of foodborne disease.[Methods]Epidemiology investigation was conducted on diarrhea patients from 3 level-II hospitals in Daxing District.The stool specimens withoutantibioticsuse were collected for isolation and identification of Vibrio cholerae,dysentery(shigella),vibrio cholerae,salmonella,and5 kinds of diarrheagenic E.coli.[Results]The cases of foodborne diseases were concentrated in the second and third quarter,the outpatient peak in sentinel hospital appeared in the third quarter.A total of 1 773 stool specimens of diarrhoea patients were col-lected in 4 years,231 strains of foodborne pathogenic bacteria were detected,with the detection rate of 13.03%,the highest one appeared in 2015(22.32%).In 4 years,114 strains of salmonella(49.35%) 41 intestinal pathogenic Escherichia coli strains(17.75%),27 strains of Shigella bacteria(11.68%),12 strains of Vibrio parahaemolyticus(5.19%),the other 17 strains of intestinal pathogenic bacteria(7.36%),20 strains of norovirus(8.66%) were detected.Foodborne disease cases were concentrated in 0-<7 and 20-<40 years age groups,accounting for 32.77% and 34.69% of monitored people.The ratio of male to female was1.3 7 ∶ 1,without significant difference(P>0.05).[Conclusion]Most cases of foodborne disease appear in the second and third quarter of Daxing District,with most patients of 0-<7 and 20-<40 years age groups,and many kinds of pathogenic microorganisms.It is necessary to enhance monitoring更多还原