【摘要】 目的:了解慢性乙型肝炎(CHB)患者中医证候虚实分类与外周血淋巴细胞亚群之间的关系。方法:将CHB患者进行证候虚证、实证及虚实夹杂证分类,并检测其外周血T、B细胞及自然杀伤(NK)细胞亚群,并对其3个证型组的指标进行分析。结果:CHB虚证、实证及虚实夹杂3个组的CD4~+T细胞百分比均较对照组低;CD8~+T细胞百分比由高至低依次为实证组、虚实夹杂证组、对照组、虚证组,实证组CD4~+/CD8~+比值显著低于虚证组或对照组,3个组的B细胞百分比均高于对照组,NK细胞百分比低于对照组。结论:CHB存在着免疫调节紊乱,证候虚实分类与外周血淋巴细胞亚群之间存在一定的相关性,中医虚实证辨证结合免疫功能检测具有一定的临床意义。更多还原

【Abstract】 Objective: Understand the patients with chronic hepatitis B( CHB) nakedness of TCM syndrome classification and the relationship between peripheral blood lymphocyte subsets. Methods: The patients with CHB were divided into asthenia syndrome( AS) group and sthenia syndrome( SS) group,deficiency and excess syndrome( DES)group,and detect the peripheral blood T and B cells and natural killer( NK) cells,the three card type group index were analyzed. Results In chronic hepatitis B,AS and SS,DES with three groups CD4~+T cell percentages are lower than normal control group,CD8~+T cell percentage were SS group > the DES group > control group > the AS group. the ratio of CD4~+/CD8~+SS group were significantly lower than the AS group or control group,the three group B lymphocyte percentage is higher than the control group,the percentage of NK cells is lower than the control group. Chronic hepatitis B have immune dysfunction,CHB of TCM classification have relationship with T and B cell subsets and NK cells,virtual empirical differentiation of TCM combined with immune function test has a certain clinical significance.更多还原