【摘要】 目的:探究比较腹腔镜与开放手术治疗直肠癌的远期疗效。方法:选择2010年9月-2011年9月在本院治疗的98例直肠癌患者,根据手术方式分为采用腹腔镜治疗的试验组50例和采用开放手术治疗的对照组48例,比较两组患者术中情况(手术时间、术中出血量、淋巴清扫数目)、术后情况(术后引流量、住院时间)、并发症发生率、肿瘤复发率及复发类型、生活质量KPS评分、患者满意率、5年生存率和平均生存时间。结果:试验组的住院时间短于对照组,且术中出血量、术后引流量均少于对照组,差异均有统计学意义(P<0.05)。两组的手术时间、淋巴结清扫数目、肿瘤复发率及复发类型、5年生存率和平均生存时间等比较,差异均无统计学意义(P>0.05)。试验组并发症发生率显著低于对照组,且生活质量评分和患者满意率均高于对照组,差异均有统计学意义(P<0.05)。结论:腹腔镜较开放手术虽不能显著延长生存期和5年生存率,但可显著优化术中情况、改善预后、减少并发症、提高生活质量,患者满意度高,故值得临床推广。更多还原

【Abstract】 Objective:To explore the long-term efficiency of laparoscopic surgery and open surgery for rectal cancer.Method:From September 2010 to September 2011,98 patients with rectal cancer in our hospital were divided into the experimental group(laparoscopic surgery,n=50) and the control group(open surgery,n=48).The intraoperative conditions(operation time,bleeding volume,the number of lymph node dissection),postoperative conditions(flow rate,length of hospital stay),the incidence of complications,tumor recurrence rate,KPS scores,patients’ satisfaction,5-year survival rate and the average survival time of two groups were compared.Result:The experimental group’s length of hospital stay was shorter than that of the control group,and the bleeding volume,flow rate were less than those of the control group,the differences were statistically significant(P<0.05).The differences of operation time,number of lymph node dissection,tumor recurrence rate,5-year survival rate and average survival time of two groups were not statistically significant(P>0.05).The incidence of complications of the experimental group was significantly lower than that of the control group,KPS scores and patients’ satisfaction were higher than that of the control group,the differences were statistically significant(P<0.05).Conclusion:The laparoscopic surgery although can not significantly prolong the survival time and 5-year survival rate,it can significantly improve the intraoperative conditions,the quality of life and the prognosis.It has lower complications incidence rate and higher patients’ satisfaction,which is worth of promoting.更多还原