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解脲脲原体感染调查及药物敏感性分析
Investigation of ureaplasmaurealyticum infection and analysis of its drug sensitivity
【摘要】 目的调查余姚地区泌尿生殖道解脲脲原体感染人群分布及药物敏感情况。方法回顾2015年6月-2016年5月泌尿生殖道感染患者Uu培养及药敏检测1 618例,分析人群分布情况及药敏检测情况。结果 Uu检出率为53.34%,女性患者检出率为55.04%,男性患者的检出率为38.42%;门诊患者占总阳性例数17.23%,住院患者占82.77%;26岁~30岁患者阳性例数最高,占总阳性例数38.18%;Uu阳性率与年龄无相关性(P>0.05)。Uu敏感率最高的5种药物依次为PRI(100%)、DOT(98.72%)、TET(96.74%)、JOS(91.50%)、CLA(78.00%);喹诺酮类的耐药率最高,CIP和OFL的耐药率分别为88.13%和71.48%。结论该地区26岁~30岁的女性是泌尿生殖道Uu感染高发人群;交沙霉素和克拉霉素为治疗Uu感染首选药物。
【Abstract】 Objective To investigate distribution of people with ureaplasmaurealyticum infection and its drug sensitivity in Yuyao area. Methods From June 2015 to May 2016,1 618 cases of urinary tract infection patients accepted Uu culture and drug sensitivity test,so as to analyze the people distribution and drug sensitivity test results. Results The detection rate of Uu was 53. 34%,among them,the detection rate of female patients was 55. 04%,and the detection rate of male patients was38. 42%; outpatients accounted for 17. 23%,hospitalized patients accounted for 82. 77%; the number of positive cases of 26-30 years old was the highest,accounting for 38. 18%; there was no correlation between the positive rate of Uu and age( P >0. 05); 5 drugs with highest sensitivity to Uu were PRI( 100%),DOT( 98. 72%),TET( 96. 74%),JOS( 91. 50%) and CLA( 78. 00%); Quinolone’s resistance rate was the highest,and the drug resistance rates of CIP and OFL were 88. 13% and71. 48%. Conclusion The 26-30 year old women are with the high incidence of Uu infection in the genitourinary tract in the region; josamycin and clarithromycin are primary choices for the treatment of Uu infection.
【Key words】 Ureaplasmaurealyticum; Uu; Population distribution; Drug sensitivity;
- 【文献出处】 中国卫生检验杂志 ,Chinese Journal of Health Laboratory Technology , 编辑部邮箱 ,2017年08期
- 【分类号】R446.5;R691.3
- 【被引频次】5
- 【下载频次】85