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妊娠期糖尿病孕妇在预产期前后引产对母儿结局的影响

Influence of Induced before or after the Expected Date of Childbirth on Pregnancy Outcomes in Patients with Gestational Diabetes Mellitus

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【作者】 陈汉青邹粟花杨建波蔡坚张颖王子莲

【Author】 CHEN Han-qing;ZOU Su-hua;YANG Jian-bo;CAI Jian;ZHANG Ying;WANG Zi-lian;Department of Obstetrics and Gynecology,The First Affiliated Hospital of Sun Yat-sen University;

【机构】 中山大学附属第一医院妇产科

【摘要】 【目的】探讨血糖控制良好的妊娠期糖尿病预产期前后引产对母儿结局的影响。【方法】回顾性分析2014年3月-2016年3月我院分娩的238例血糖控制良好的妊娠期糖尿病病例。血糖控制良好的病例为仅需饮食控制、运动治疗、无需药物治疗。妊娠40周-40+6周引产为研究组120例,妊娠39周-39+6周引产为对照组118例。【结果】两组病例的剖宫产率无明显差异(49.2%vs.55.9%,P=0.528),产后出血发生率无显著差异(10.0%vs 14.4%,P=0.299);两组病例新生儿体质量无明显统计学差异[(3.26±0.33)kg vs(3.22±0.34)kg,P=0.448],胎儿宫内窘迫发生率、大于胎龄儿发生率、新生儿病理性黄疸发生率、新生儿低血糖的发生率等也无统计学差异(P>0.05)。【结论】不需药物治疗、血糖控制良好、无并发症的妊娠期糖尿病患者孕40周前或后引产剖宫产率无增加,围产结局无差异,可根据具体情况预产期前或后引产。

【Abstract】 【Objective 】To investigate the influence of induced before or after the expected date of childbirth on maternal and neonatal outcome in patients with gestational diabetes mellitus which blood glucose well controlled.【Methods】We retrospectively analyzed 238 cases with mild gestational diabetes mellitus who had delivered in this hospital. Mild gestational diabetes mellitus cases were those who only need diet control,exercise therapy,no drug treatment. There were 120 cases who induced in 40 ~ 40+ 6weeks was the research group,and 118 cases who induced in 39 ~ 39+6weeks was the control group.【Results】The cesarean section rate between the two groups was no difference(49.2% vs 55.9%,P = 0.528);Postpartum hemorrhage rate of the two groups was no difference(10.0%vs14.4%,P=0.299)Birth weight between the two groups was no difference(3.26 ± 0.33)kg vs(3.22 ± 0.34)kg,P =0.448). The incidences of the two groups including fetal distress,large for gestational age infants,neonatal pathological jaundice,neonatal hypoglycemia were no difference(P > 0.05).【Conclusion】Pregnant women with mild gestation diabetes mellitus induced before after 40 completed gestation weeks did not increase cesarean section rate. Pregnancy outcome between the two groups were no difference.It would be better to select the appropriate induction time according to the patient′s condition.

【基金】 中山大学5010计划项目(2012004)
  • 【文献出处】 中山大学学报(医学科学版) ,Journal of Sun Yat-sen University(Medical Sciences) , 编辑部邮箱 ,2017年01期
  • 【分类号】R714.256
  • 【被引频次】19
  • 【下载频次】185
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