【摘要】 目的分析胸腔镜胸膜固定术治疗大量恶性胸腔积液(MPE)的临床疗效及安全性。方法 98例大量恶性胸腔积液患者作为研究对象,使用随机数表法分为对照组与观察组,各49例。给予对照组胸腔闭式引流术,给予观察组胸腔镜胸膜固定术,进行为期12周的随访,对比两组治疗效果及并发症发生情况。结果观察组总有效率为95.92%,明显高于对照组的73.47%,差异具有统计学意义(P<0.05);观察组并发症发生率为6.12%,低于对照组22.45%,差异具有统计学意义(P<0.05)。结论大量恶性胸腔积液患者采用胸腔镜胸膜固定术治疗的临床疗效显著优于胸腔闭式引流术,兼具较高安全性,值得推广。更多还原

【Abstract】 Objective To analyze clinical effect and safety by thoracoscopic pleurodesis in the treatment of massive malignant pleural effusion(MPE). Methods A total of 98 patients with massive malignant pleural effusion were divided by random number table into control group and observation group, with 49 cases in the each group. The control group received thoracic closed drainage, and the observation group received thoracoscopic pleurodesis. Follow-up lasted for 12 weeks. Comparison was made on curative effects and complications between the two groups. Results The observation group had obviously higher total effective rate s 95.92% than 73.74% in the control group, and the difference had statistical significance(P<0.05). The observation group had lower incidence of complications as 6.12% than 22.45% in the control group, and the difference had statistical significance(P<0.05). Conclusion Implement of malignant pleural effusion for patients with massive malignant pleural effusion provides remarkably better clinical effect than thoracic closed drainage, along with high safety. This method is worth promoting.更多还原