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注射用骨肽与阿仑膦酸钠用于骨质疏松症患者治疗中的临床效果

Clinical effect of ossotide for injection and alendronate sodium in the treamment of osteoporosis patients

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【作者】 施鹏旭李玥婷华凯路宝民郭庆升

【Author】 SHI Peng-xu;LI Yue-ting;HUA Kai;Department of Orthopaedics,Liaoning Province People’s Hospital;

【机构】 辽宁省人民医院骨科辽宁省肿瘤医院乳腺外科

【摘要】 目的研究注射用骨肽与阿仑膦酸钠用于骨质疏松症治疗的临床效果。方法 100例骨质疏松症患者,随机分为观察组与对照组,各50例。对照组采用阿仑膦酸钠联合钙尔奇D进行治疗,观察组患者采用注射用骨肽联合阿仑膦酸钠进行治疗,比较两组患者的临床疗效。结果观察组患者的临床治疗总有效率为94.00%,显著高于对照组的64.00%,差异有统计学意义(P<0.05)。治疗前,两组患者Wards三角(Wards)、大粗隆(Troch)及左侧股骨颈(Neek)的骨密度比较,差异无统计学意义(P>0.05)。治疗后,观察组患者Wards、Troch及Neek的骨密度显著高于对照组,差异有统计学意义(P<0.05)。结论注射用骨肽与阿仑膦酸钠用于骨质疏松症治疗的临床效果显著,值得广泛推广。

【Abstract】 Objective To study the clinical effect of ossotide for injection and alendronate sodium in the treamment of osteoporosis patients.Methods A total of 100 osteoporosis patients were randomly divided into observation group and control group,with 50 cases in each group.The control group received alendronate sodium combined with caltrate D for treatment,and the observation group received ossotide for injection combined with alendronate sodium for treatment.Clinical effect was compared in two groups.Results The observation group had total clinical treatment effective rate as 94.00%,which was obviouslyl higher than 64.00%in the control group,and the difference had statistical significance(P<0.05).There were no statistically significant difference in bone mineral density of wards triangle(Wards),trochanter major(Troch) and left side of femoral neck(Neek) before treatment in two groups(P>0.05).After treatment,the observation group had obviously higher bone mineral density of Wards,Troch and Neek than that of the control group,and the difference had statistical significance(P<0.05).Conclusion Ossotide for injection and alendronate sodium shows significant clinical effect in the treamment of osteoporosis patients,and it is worth wide promotion.

  • 【文献出处】 中国实用医药 ,China Practical Medicine , 编辑部邮箱 ,2017年04期
  • 【分类号】R580
  • 【被引频次】3
  • 【下载频次】54
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