【摘要】 目的探讨老年发热伴血小板减少综合征(SFTS)发生多器官功能障碍(MODS)的临床特点。方法收集59例老年SFTS患者资料进行回顾性分析,按预后分为存活组(50例)和死亡组(9例)。比较两组患者多器官功能损害的发生及转归,探讨影响其预后的相关因素。结果 59例患者均出现MODS,其中治愈者50例,病死9例,2例患者因病情危重放弃进一步治疗而自动出院(将自动出院病例归入死亡组),病死率为18.64%(11/59)。存活组与死亡组患者的心脏、肝脏、肾脏和脑等器官受损评分差异具有统计学意义(P均<0.05);随着器官损害数量增加,病死率随之增高。患者受损器官严重程度、男性、高热(≥39.0℃)、热程>3 d以及发病后就诊晚(≥6 d)等因素,与预后不良存在显著相关性。结论器官损害严重度、男性、高热、热程及就诊时间延迟等是预后不良、死亡风险增加的危险因素。更多还原

【Abstract】 Objective To investigate the clinical characteristics of multiple organ dysfunction syndrome(MODS) in elderly patients with fever and thrombocytopenia syndrome(SFTS).Methods The clinical data of 59 cases with SFTS in elderly patients were analyzed,retrospectively.The cases were divided into survival group(50 cases) and death group(9 cases) according to the prognosis.The occurrence and prognosis of multiple organ damage were analyzed,while the related indicators of the prognosis were explored.Results All the 59 patients had MODS,among whom,50 cases were cured,and 9 cases died;and 2cases were discharged from the hospital(divided into the death group).The mortality rate was 18.64%(11/59).Compared with the survival group,the injury severity scores of the heart,liver,kidney,brain and other organs of patients in death group were significantly higher,with significant differences(all P < 0.05).With the increased number of organ damage,the fatality rate increased.The degree of damages of organs,male,high fever(≥ 39.0 ℃),fever duration > 3 days and delay to the hospital(≥ 6 days) were associated with the mortality.Conclusions The degree of organ damage,male,high fever,and the delay to the hospital were the risk factors to the poor prognosis and death.更多还原