Myocardial hypertrophy,a compensatory and adaptive response of the heart,resulted from the heart's adapting to the overloading pressure. Pathological hypertrophy in left ventricle is prevalent in various cardiovascular diseases such as hypertension,arrhythmia and would even cause sudden cardiac death. Many influence factors could result in left ventricular hypertrophy,such as mechanical factors,nervous-humoral factors,cytokines,and signal pathways; they form a complex regulatory network,therefore drug combi...
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